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Table 1 Affinity determination of 7G6 and E2814 antibodies to wild type tau protein

From: Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer’s disease

Antibodyka(1/Ms)kd(1/s)KD (M)
7G6 (mouse)3.11 × 1061.95 × 10−46.36 × 10−11
E2814 (human)3.50 × 1063.07 × 10− 48.81 × 10− 11