Table 1 Summary of clinical features, VAF of H3F3A K27M and relative H3 K27M fluorescence intensity
Case Number | Age at onset | Sex | Tumor location | VAF of H3F3A K27M (%) | Relative H3 K27M fluorescence intensity(Median) |
|---|---|---|---|---|---|
1 | 6 | F | Pons | 40.7 | aN/A |
2 | 30 | F | Insular gyrus | 42.4 | 1.13 |
3 | 53 | M | Brainstem, Temporal lobe | 0.8 | 0.23 |
4 | 14 | M | Spinal Cord | 38.3 | 1.27 |
5 | 37 | M | Brainstem | 73.2 | 1.80 |
6 | 37 | F | Thalamus, Ventricle, Midbrain | 40.7 | 1.07 |
7 | 15 | F | Basal ganglia | 29.6 | aN/A |
8 | 29 | M | Thalamus | 13.1 | 0.52 |
9 | 31 | F | Thalamus | 42.8 | aN/A |
10 | 14 | M | Spinal Cord | 68.0 | 1.98 |
11 | 9 | F | Brainstem | 22.7 | 0.81 |
12 | 31 | F | Brainstem, Thalamus, Cerebellum | 79.9 | 1.50 |
13 | 14 | M | Thalamus | 49.6 | aN/A |
14 | 24 | M | Corpus callosum | 43.0 | aN/A |
15 | 21 | M | Corpus callosum | 65.9 | 1.09 |