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Table 1 Summary of clinical features, VAF of H3F3A K27M and relative H3 K27M fluorescence intensity

From: H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant

Case NumberAge at onsetSexTumor locationVAF of H3F3A K27M (%)Relative H3 K27M fluorescence intensity(Median)
16FPons40.7aN/A
230FInsular gyrus42.41.13
353MBrainstem, Temporal lobe0.80.23
414MSpinal Cord38.31.27
537MBrainstem73.21.80
637FThalamus, Ventricle, Midbrain40.71.07
715FBasal ganglia29.6aN/A
829MThalamus13.10.52
931FThalamus42.8aN/A
1014MSpinal Cord68.01.98
119FBrainstem22.70.81
1231FBrainstem, Thalamus, Cerebellum79.91.50
1314MThalamus49.6aN/A
1424MCorpus callosum43.0aN/A
1521MCorpus callosum65.91.09
  1. aN/A not available