Skip to main content

Table 1 Demographic, pathological and clinical data of CFAS brain donors

From: Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain

Case Age (y) Gender PMI (h) Brain pH Braak stage CERADa Thal Phase CAA Dementia1at death Cause of death2
C1 87 F 60 6.1 II None 1 No No Depressive episode, unspecified
C2 92 M 33 6.8 II None 2 Yes Yes Chronic ischaemic heart disease
C3 74 M N/A 6.3 II Moderate 2 No No Acute myocardial infarction
C4 75 M 29 7.3 0 Mild 3 Yes No Acute myocardial infarction
C5 73 F 20 6.5 0 None 0 No No Amyloidosis
C6 78 F 17 6.9 I None 1 No No Pulmonary embolism
D1 73 M 104 6.2 II None 0 Yes No Cellulitis, unspecified
D2 76 M 16 6.6 II Moderate 2 Yes No Chronic ischaemic heart disease
D3 75 F 5 6.3 I None 2 No No Acute myocardial infarction
D4 73 M 23 6.9 I None 1 Yes No Interstitial pulmonary disease with fibrosis
D5 84 F 12 7.3 II None 3 Yes No Chronic ischaemic heart disease
D6 91 M 36 6.4 II None 0 Yes No Unspecified diabetes mellitus without complications
  1. C, control; CFAS, Cognitive Function and Ageing Study; D, diabetic (type 2 diabetes mellitus); F, female; h, hour; M, male; PMI, post-mortem interval; y, year; CAA, cerebral amyloid angiopathy present or absent
  2. aCERAD maximum neuritic plaque score
  3. 1Dementia status at death
  4. 2Cause of death as recorded from death certification data
Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us