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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain

Fig. 3

a Astrocyte- and b endothelial cell-enriched IMPaLA pathways in the KEGG database. Up-regulated genes are represented by the white bars and down-regulated genes are represented by the black bars. Signalling pathways, other includes a Sphingolipid, oxytocin, Rap1, neurotrophin, ErbB, phosphatidylinositol, MAPK, chemokine, T cell receptor, GnRH, Ras, AMPK, mTOR, PI3K-Akt, oestrogen, Wnt, and p53 and b PI3K-Akt, oxytocin, phospholipase D, GnRH, Rap1, MAPK, thyroid hormone, cGMP-PKG, and Wnt signalling pathways. *P < 0.05, **P < 0.01, ***P < 0.001

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