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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: A pilot radiogenomic study of DIPG reveals distinct subgroups with unique clinical trajectories and therapeutic targets

Fig. 5

Genomic comparison between PD and PR post-RT response groups, based on Gene Set Enrichment Analysis (GSEA) and GO term enrichment analysis. a GSEA results, in which the total height of the curve reflects the extent of gene enrichment within given biological pathways, with corresponding normalized enrichment score (NES) and false discovery rate (FDR) reported. Upregulated genes in epithelial-mesenchymal transition and hypoxia pathways are enriched in the PD compared to PR post-RT response groups. b GO term enrichment analysis results, illustrating differential expression of genes associated with inflammation and immune-mediated pathways between the PD and PR post-RT response groups. The size of dot reflects the number of genes identified in each gene set

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Acta Neuropathologica Communications

ISSN: 2051-5960

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