Fig. 2

Tumor-associated pericytes represent the major cell type that expresses FAP in GBM. a, b Double immunohistochemistry (IHC) of FAP (red)/PDGFR (blue), and FAP (red)/nestin (blue) in MGG90 (a) and MGG125 GBM (b). Left, Representative IHC images of parenchymal and perivascular areas. Right, Quantification of the fraction of double positive cells. Arrows point to representative double positive cells (dark purple)