Fig. 2

H3.3G34V Co-enriches With Wild-type H3.3. a Relative proportion of H3.3WT enrichment across gene elements with H3.3G34V expression or knock-down. b H3.3 enrichment at SOX2 was greatest KNS42 cell s expressing H3.3G34V, compared to NHAs lacking H3.3G34V expression (red highlight) or after H3.3G34V transduction. c, d Co-enrichment of H3.3G34V and H3.3WT was observed across experimental conditions at the top 10,000 loci most-enriched for C) H3.3G34V, and D) H3.3WT in transduced KNS42 cells without DOX induction. e When the top 10,000 loci most enriched for H3.3G34V, H3.3 wild-type, H3K36me3 and H3K27me3 in transduced KNS42 cells without DOX induction are compared, greatest overlap is observed between H3.3G34V and wild-type H3.3 enrichments patterns, with 3041 common loci between these two groups