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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Isotope-reinforced polyunsaturated fatty acids improve Parkinson’s disease-like phenotype in rats overexpressing α-synuclein

Fig. 4

Treatment with D-PUFAs restores mitochondrial function in AAV-A53T α-syn-transduced rats. a Western blot for respiratory chain complexes in the rat SN. D-PUFAs preserve complex I immunoreactivity in the ipsilateral hemisphere. b Densitometric analysis of each band was used to calculate the relative abundance of the target proteins. c mtDNA copy number was determined by RT-qPCR analysis. Bar graphs depict mean values ± SEM of three animals per group analyzed using two-way ANOVA followed by Tukey’s post-hoc multiple comparisons test. *p < 0.05

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Acta Neuropathologica Communications

ISSN: 2051-5960

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