Prenatal alcohol exposure is a leading cause of interneuronopathy in humans

Table 1 Gestational age/postnatal age and cause of death of selected control cases

Case number	Term	Cerebral maturation*	TOP	Cause of death
1	15 WG	14 WG	Yes	Atrioventricular canal
2	16WG	16WG	Yes	Isolated sacral myelomeningocele
3	22 WG	20 WG	No	IUFD
4	22 WG	22 WG	Yes	Obstructive uropathy
5	24 WG	24 WG	No	IUFD
6	26 WG	26 WG	Yes	Hereditary bilateral microphtalmia
7	28 WG	28 WG	Yes	Severe distal arthrogryposis
8	30 WG	30 WG	No	Cord prolapse
9	32 WG	32 WG	Yes	Complex cardiac malformation
10	34 WG	34 WG	Yes	Suspected vermis hypoplasia (Not confirmed)
11	35 WG	35 WG	No	Non immune fetal hydrops Caesarean section
12	36 WG	36 WG	No	Bilateral renal agenesis Fallot tetralogy Immediate postpartum death
13	36 WG	36 WG	No	Dilated cardiomyopathy Dead at day 2
14	37 WG	37 WG	No	Normal pregnancy Death despite resuscitation No autopsy and placental abnormalities
15	39 WG	39 WG	No	Perpartum in utero death Placental membrane praevia vessel rupture
16	3 months PN	3 months PN	No	Prone position sleep
17	2 years and 11 months	3 years	No	Anaphylactic shock

IUFD in utero fetal death, PN post-natal, TOP Medical termination of pregnancy, WG weeks’gestation
*According to the morphometric criteria of Guihard-Costa and Larroche [19]

ISSN: 2051-5960