Fig. 4
C11orf95-RELA fusion variants present diverse oncogenic potential. a Schematic presentation of the predicted protein products of various RELAFUS variants with HA tag in the C-terminus in the pTomo-lentiviral vectors. Zn, zinc finger domain. b and c Kaplan–Meier survival curves and Summary of RELAFUS-HA-induced brain tumors. Lentiviruses were injected into neonatal pups brain in Nestin-Cre+/−;Cag-Cas9+/+ mice (n.s., not significant, *p < 0.05, ***p < 0.001. M, medium titer; n/a, not applicable)