Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice

Table 1 Proteins that interact with TTBK1

TTBK1 Bait Region	Interacting gene	Protein name	Cellular function
Domain A	GABARAP	Gamma-aminobutyric Acid Receptor—Associated Protein	GABA receptor transport, autophagosome maturation
	GABARAPL2	Gamma-aminobutyric Acid Receptor—Associated Protein	Intra-golgi trafficking, autophagosome maturation
	ITSN2	Intersectin 2	Endocytic membrane trafficking, microtubule assembly, dendrite formation
	PTPRK	Protein-Tyrosine Phosphatase Kappa	Cell contact and adhesion
Domain B	SMS	Spermine Synthase	Spermine to spermidine catalysis
	XRCC6	X-ray Repair Cross Complementing Protein 6	Helicase, DNA damage repair, innate immune response

ISSN: 2051-5960