Fig. 7
From: Is the eye a window to the brain in Sanfilippo syndrome?
Relationship between the age of onset and rate of accumulation of disease lesions in the MPS IIIA mouse brain (squares) and retina (circles). Data indicating enlargement of the LIMP2-positive endo/lysosomal compartment (a–c), presence of activated microglia (d, e) and elevated expression of GFAP by macroglia (f, g) is shown. The slope of the lines was compared, and p values have been tabulated