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Table 3 Morphological characterization of single and multiple triads

From: In vivo RyR1 reduction in muscle triggers a core-like myopathy

 

Single (CTRL)

Multiple (RyR1-Rec)

Student t test

% CTRL

Mean

SEM

n

Mean

SEM

n

TT width (nm)

26.0

0.5

140

52.7

1.6

135

p < 0.001*

202

SR width (nm)

77.5

0.8

239

85.2

1.2

107

p < 0.001*

110

SR-TT space (nm)

20.6

0.3

135

20.5

0.4

138

0.9

100

  1. The size of T-tubules, SR and intermembranes space thickness were measured as presented on Additional file 1: Fig. S5
  2. *Represent significant data
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Acta Neuropathologica Communications

ISSN: 2051-5960

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