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Table 3 List of genes associated with recurrence in lactotroph tumors selected using CGH array (univariate and multivariate analysis) and transcriptomic analysis

From: Chromosomal instability in the prediction of pituitary neuroendocrine tumors prognosis

Gene Chromosome aCGH univariate logistic regressions aCGH multivariate logistic regressionsb Transcriptomic analysis
LRT raw p-values LRT adjusted p-valuesa LRT raw p-values LRT adjusted p-valuesa Fold-Change T-test p-values
ACTL8 1 0.003 0.041 0.003 0.046 10.955 0.004
ALDH3B1 11 0.005 0.041 0.012 0.099 2.194 0.033
AMBRA1 11 0.002 0.041 0.002 0.046 3.642 0.033
ATPAF1 1 0.005 0.041 0.003 0.046 − 2.104 0.016
CEL 9 0.001 0.041 0.003 0.046 2.392 0.004
CLCNKA 1 0.003 0.041 0.003 0.046 9.043 0.012
DLG2 11 0.005 0.041 0.012 0.099 − 2.146 0.027
DOCK7 1 0.005 0.041 0.003 0.046 2.100 0.000
DPAGT1 11 0.005 0.041 0.012 0.099 6.217 0.001
ELAVL4 1 0.005 0.041 0.003 0.046 2.786 0.039
FPGT-TNNI3K 1 0.003 0.041 0.003 0.046 2.064 0.036
FRMD8 11 0.005 0.041 0.012 0.099 25.132 0.007
GSTM4 1 0.003 0.041 0.003 0.046 19.111 0.019
HECTD3 1 0.005 0.041 0.003 0.046 2.465 0.002
HMGCL 1 0.001 0.041 0.003 0.046 − 2.135 0.017
HSD17B12 11 0.002 0.041 0.002 0.046 − 2.021 0.016
HSPB7 1 0.003 0.041 0.003 0.046 10.999 0.012
HTATIP2 11 0.002 0.041 0.002 0.046 − 2.014 0.008
KCNJ5 11 0.005 0.041 0.012 0.099 − 2.514 0.002
LAPTM5 1 0.003 0.041 0.003 0.046 − 2.272 0.034
LPL 8 0.000 0.041 0.001 0.046 2.578 0.003
MAST2 1 0.005 0.041 0.003 0.046 2.094 0.023
MDK 11 0.002 0.041 0.002 0.046 − 2.180 0.041
NRIP3 11 0.002 0.041 0.002 0.046 2.076 0.020
PAMR1 11 0.002 0.041 0.002 0.046 − 2.563 0.048
PGM2L1 11 0.005 0.041 0.012 0.099 2.222 0.013
PHOX2A 11 0.005 0.041 0.012 0.099 52.058 0.007
PIFO 1 0.003 0.041 0.003 0.046 2.751 0.001
PLA2G2F 1 0.003 0.041 0.003 0.046 3.403 0.047
POMGNT1 1 0.005 0.041 0.003 0.046 15.479 0.047
PRKAA2 1 0.005 0.041 0.003 0.046 2.568 0.002
RHCE 1 0.003 0.041 0.003 0.046 − 2.184 0.017
RPUSD4 11 0.005 0.041 0.012 0.099 2.011 0.001
RUNX3 1 0.003 0.041 0.003 0.046 − 2.438 0.003
SCGB1D2 11 0.005 0.041 0.012 0.099 2.155 0.005
SOX6 11 0.001 0.041 0.001 0.046 37.554 0.000
SRSF8 11 0.005 0.041 0.012 0.099 − 2.223 0.010
ST3GAL3 1 0.005 0.041 0.003 0.046 11.519 0.000
TARDBP 1 0.003 0.041 0.003 0.046 2.117 0.001
TMEM216 11 0.005 0.041 0.012 0.099 − 2.006 0.009
  1. Bold character correspond to significant adjusted p-values of aCGH multivariate logistic regressions
  2. LRT likelihood ratio test
  3. aBenjamini-Hochberg
  4. aAdjusted for age at diagnosis, sex, histologic grade