Skip to main content

Table 2 Univariate analysis for mutational statuses of genes mutated in ≥ 10% cases in adult medulloblastoma cohort

From: Clinical and mutational profiles of adult medulloblastoma groups

Gene Mutational frequency (%) OS log-rank p value Benjamini–Hochberg q value
TERT promoter 39a 0.294 0.460
KMT2D 31 0.056 0.334
TCF4 31 0.282 0.460
KMT2C 30 0.002 0.034
PTCH1 27 0.356 0.460
DDX3X 24 0.969 0.969
CTNNB1 20 0.565 0.640
BRCA2 17 0.337 0.460
TP53 16 0.062 0.334
FBXW7 14 0.118 0.334
SMO 14 0.101 0.334
NOTCH1 13 0.379 0.460
SMARCA4 13 0.172 0.418
PDGFRA 11 0.873 0.928
MED12 11 0.102 0.334
SETD2 11 0.257 0.460
CREBBP 10 0.314 0.460
  1. Bold values are p<0.05 and q<0.05
  2. a34/88 cases by Sanger sequencing