Clinical and mutational profiles of adult medulloblastoma groups

Table 2 Univariate analysis for mutational statuses of genes mutated in ≥ 10% cases in adult medulloblastoma cohort

Gene	Mutational frequency (%)	OS log-rank p value	Benjamini–Hochberg q value
TERT promoter	39^a	0.294	0.460
KMT2D	31	0.056	0.334
TCF4	31	0.282	0.460
KMT2C	30	0.002	0.034
PTCH1	27	0.356	0.460
DDX3X	24	0.969	0.969
CTNNB1	20	0.565	0.640
BRCA2	17	0.337	0.460
TP53	16	0.062	0.334
FBXW7	14	0.118	0.334
SMO	14	0.101	0.334
NOTCH1	13	0.379	0.460
SMARCA4	13	0.172	0.418
PDGFRA	11	0.873	0.928
MED12	11	0.102	0.334
SETD2	11	0.257	0.460
CREBBP	10	0.314	0.460

ISSN: 2051-5960