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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication”

Fig. 4

Methylation-based t-SNE distribution. The two tumors with EP300:BCOR fusion were compared with 147 reference samples from the Heidelberg cohort belonging to the HGNET-BCOR, HGNET-MN1, LGG-MYB/MYBL, EPN-RELA, EPN-YAP methylation classes which constitute histopathological differential diagnoses. The two cases of this study are indicated as grey dots and shown by arrows. HGNET-BCOR, high-grade neuroepithelial tumors with BCOR alteration (red dots); HGNET-MN1, high-grade neuroepithelial tumors with MN1 alteration (yellow dots); LGG-MYB/MYBL1, low-grade gliomas with MYB or MYBL1 alteration (blue dots); EPN-RELA, ependymomas with RELA fusion (pink dots); EPN-YAP, ependymomas with YAP fusion (gree dots)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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