Table 2 Summary of iPSC cell lines used in this study
From: RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3
Cell line | Condition | Sex | Age | Reprogramming method | Source/References |
|---|---|---|---|---|---|
18a (Ctrl #1) | Non-neurological control | Female | 51 | Retrovirus | Boulting et al. [63]; Nat Biotechnol |
11a (Ctrl #2) | Non-neurological control | Male | 36 | Retrovirus | Boulting et al. [63]; Nat Biotechnol |
15-12 (Ctrl #3) | Non-neurological control | Male | 36 | Sendai | RUCDR Infinite Biologics |
CS0002 (Ctrl#4) | Non-neurological control | Male | 51 | Episomal | Cedars Sinai/Answer ALS |
C9#3.1 (C9-ALS #1) | C9-ALS | Female | 64 | Sendai | RUCDR Infinite Biologics |
C910689 (C9-ALS #2) | C9-ALS | Female | 51 | Sendai and episomal | Coriell Institute for Medical Research |
C9#2 (C9-ALS #3) | C9-ALS | Female | 61 | Sendai | RUCDR Infinite Biologics |