Fig. 1

EZHIP expression in diffuse midline gliomas. A distinct H3K27me3 loss (A, magnification, ×400) in one case of diffuse midline glioma with EZHIP overexpression, without expression of H3K27-mutant protein (B, magnification, ×400) and with strong positive EZHIP expression (C, magnification, ×400). A case of diffuse midline glioma, H3K27-mutant with a loss of expression of H3K27me3 (D, magnification, ×400), nuclear expression of H3K27-mutant protein (E, magnification, ×400), and without expression of EZHIP (F, magnification, ×400). DMG diffuse midline glioma, WT wildtype. Black scale bars represent 50 μm