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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: A novel recessive mutation affecting DNAJB6a causes myofibrillar myopathy

Fig. 4

Assessment of motor function in the HOM and WT mice. a Body weight curves showing changes in body weight over 18 months for HOM and WT mice. Shown are mean ± SEM (n = 12–15) b Hanging test showing “minimal holding impulse” (body mass x hang time), in seconds (s) x gram (g), in 3, 6, 9, 12, 18-month old HOM mice and WT littermates. c Mean score in grip strength over time in HOM mice and WT littermates. d Treadmill experiments shown by duration of running, in seconds (s), before showing signs of exhaustion in HOM mice and WT littermates. e Rotarod performance showing mean duration, in seconds (s), spent on the accelerating rotating rod at 3, 6, 9, 12,18-month old HOM and WT mice. Values represent mean ± SEM (n = 12–15). P value = * < 0.05, ** < 0.01

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