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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Nilvadipine suppresses inflammation via inhibition of P-SYK and restores spatial memory deficits in a mouse model of repetitive mild TBI

Fig. 6

a Immunofluorescent imaging of CD68 in corpus callosum. b Quantification of the fluorescent intensity of CD68 signal demonstrated an increased distribution of CD68 macrophages in the TBI-vehicle mice compared to controls (\(p<0.0001\)) and a decreased signal after treatment with nilvadipine (\(p<0.001\)). Distribution (M-male, F-female): sham-vehicle n = 4 (2M, 2F), r-mTBI-vehicle n = 4 (1M, 3F), sham-nilvadipine n = 4 (1M, 3F), r-mTBI-nilvadipine n = 4 (2M, 2F). Data were analyzed using one-way ANOVA. Scale bars equal 100 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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