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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas

Fig. 6

Cox-PH model and AIC analysis restricted to lower grade tumors fails to identify an appropriate CDKN2A cutoff. For primary grade 2/3 tumors, neither CDKN2A homozygous deletion (a, orange line) nor histologic grade (blue line) were significant predictors of outcome across the range of tested values (HR ≤ 1, p values > 0.05). CDKN2A deletion is also not a significant predictor in grade 2/3 first recurrence tumors (b, HR ≤ 1, p values > 0.05), while histologic grade is significant in this cohort

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