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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role

Fig. 2

Association of LP protein deficiency with the behavioral outcome of traumatized mice over 4 weeks. a The health score was obtained by rating mice from 4 (good outcome) to 1 (bad outcome) based on quartiles of the neuroscore and beam walk values over the 4 weeks of observation. The final score was the sum of the weighted scores of the two parameters, e.g. the neuroscore and beam walk each accounted for 50% of the final score. b Association (odds ratio; 95% confidence interval) between the genotype and health score. The odds ratio was calculated by a Chi square test using the Woolf logit interval for calculating the 95% confidence interval (CI 95%), stratifying mice in terms of good outcome (defined as a score ≥ 3) versus bad outcome (score < 3). MASP-2−/−, MBL−/− and FCN-A−/− mice were significantly associated with good outcome scores

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