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Table 1 Association between a polygenic score for longer telomere length and risk of ependymoma in the California Cancer Record Linkage Project case–control dataset (ages 0–19)

From: Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

Logistic regression model Cases/controls OR (95% CI)a P-value  
All patients combined 153/696 1.12 (0.94–1.34) 0.207  
Childhood-onsetc 114/696 0.99 (0.81–1.21) 0.939 Pcase-case = 0.021b
Adolescent-onsetd 39/696 1.67 (1.18–2.37) 3.97 × 10−3
  1. Nominally significant P values < 0.05 in bold
  2. aAdjusted for sex and 10 principal components
  3. bP-value corresponding to the association between a polygenic score for longer telomere length and age at diagnosis (< 12 vs. ≥ 12) in a case-only analysis of ependymoma patients
  4. cless than 12 years of age at diagnosis
  5. d12–19 years of age at diagnosis