Fig. 1

Per-allele association of ependymoma risk (y-axis) and leukocyte telomere length (x-axis) at eight SNPs known to influence telomere length, with the slopes of fitted lines equal to the inverse-variance weighted (IVW) Mendelian randomization estimate (solid line) and the MR-Egger estimate (dashed line) in a Toronto EPN-PF-A case–control data; b CCRLP childhood-onset (< 12 years) ependymoma case–control data; c CCRLP adolescent-onset (12–19 years) ependymoma case–control data; d Glioma International Case-Control Consortium (GICC) adult-onset ependymoma case–control data