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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical severity

Fig. 2

DPR protein concentrations across different brain regions. Soluble (ac) and insoluble (df) poly-GP, poly-GA and poly-GR levels are depicted across frontal cortex (FC), temporal cortex (TC), occipital cortex (OC) and cerebellum (Cb). The homozygous C9orf72 mutation case is shown in red. All data are mean ± SEM. Statistical analysis: Friedman test followed by Dunn’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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