Fig. 1

Comparison of soluble (S) and insoluble (INS) DPR levels. Poly-GP (a), poly-GA (b) and poly-GR (c) concentrations in frontal cortex (Frontal), temporal cortex (Temporal), occipital cortex (Occipital) and cerebellum (Cerebellum). For each area, soluble fractions are shown as the left bar with individual data points represented as diamonds (◇) and insoluble fractions are shown as the right bar with individual data points illustrated as circles (•). All data are mean ± SEM. For statistical analyses see Figs. 2 and 3. The homozygous C9orf72 repeat expansion case is shown in red