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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Assessment of genetic risk for improved clinical-neuropathological correlations

Fig. 1

Relationship between polygenic scores and pathological diagnostic categories. Significant difference from: *Control, †All AD groups (AD, AD + DLB, and AD + MTLS) based on Bonferroni corrected multinomial regression models. ‡The number of participants is reported for the AD PHS and PD PRS analyses. The DLB PRS was analyzed in a subset of 2282 total participants. Abbreviations: PD, Parkinson’s disease, PRS, polygenic risk score; DLB, dementia with Lewy bodies; AD, Alzheimer’s disease; PHS, polygenic hazard score; FTD, frontotemporal lobar degeneration; MTLS, medial temporal lobe sclerosis

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