Fig. 10

Age-related motor impairment in Drosophila co-expressing DPRs. a–d Median climbing speed of adult Drosophila co-expressing DPRs under the control of a single copy of the pan-neuronal driver nSyb-Gal4 (nSyb-Gal4/+) at 7 days post-eclosion. e–h Median speed of adult Drosophila co-expressing DPRs under the control of a single copy of the pan-neuronal driver nSyb-Gal4 (nSyb-Gal4/+) at 28 days post-eclosion. Error bars = SEM. ANOVA with post hoc Tukey’s multiple comparison between groups ****p < .0001; ***p < .001; **p < .01; *p < .05. Each point represents an individual fly. Motor assays were performed from at least 3 independent crosses per genotype