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Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila

Fig. 10

Age-related motor impairment in Drosophila co-expressing DPRs. a–d Median climbing speed of adult Drosophila co-expressing DPRs under the control of a single copy of the pan-neuronal driver nSyb-Gal4 (nSyb-Gal4/+) at 7 days post-eclosion. e–h Median speed of adult Drosophila co-expressing DPRs under the control of a single copy of the pan-neuronal driver nSyb-Gal4 (nSyb-Gal4/+) at 28 days post-eclosion. Error bars = SEM. ANOVA with post hoc Tukey’s multiple comparison between groups ****p < .0001; ***p < .001; **p < .01; *p < .05. Each point represents an individual fly. Motor assays were performed from at least 3 independent crosses per genotype

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