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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: BRAF V600E mutation mediates FDG-methionine uptake mismatch in polymorphous low-grade neuroepithelial tumor of the young

Fig. 2

Histopathologic and genomic features of a patient with PLNTY. a Hematoxylin and eosin (H&E) staining (top) and CD34 immunohistochemistry (bottom) in the high-methionine-uptake (#1) and low-methionine-uptake (#2) region within tumor tissue. Bars, 50 μm. b Sanger sequencing for detection of BRAF V600E (arrow, left) and IDH1 R132H (arrow, right) mutations. c Fluorescence in situ hybridization for detection of 1p31/1q25 (left) and 19q13/19p13 (right) chromosomal deletions

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