From: New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma
Epidemiological-clinical data | ||
---|---|---|
Total cohort | 301 | |
Gender | Male | 175 pts (58.1%) |
Female | 126 pts (41.9%) | |
M:F | 1.4 | |
Age (years) | Range | 20-86 |
Median | 64 | |
< 30 years | 10 pts (3.3%) | |
≥ 30 years | 291 pts (96.7%) | |
Diagnosis (WHO 2016) | ||
Common Gliomas | Diffuse astrocytoma, IDH-wt (grade II) | 6 |
Diffuse astrocytoma, IDH-mut (grade II) | 10 | |
Anaplastic astrocytoma, IDH-wt (grade III) | 6 | |
Anaplastic astrocytoma, IDH-mut (grade III) | 10 | |
Glioblastoma, IDH-wt (grade IV) | 241 | |
Glioblastoma, IDH-mut (grade IV) | 10 | |
Oligodendroglioma, IDH-mut and 1p/19q-codeleted (grade II) | 7 | |
Anaplastic oligodendroglioma, IDH-mut and 1p/19q-codeleted (grade III) | 8 | |
Uncommon Gliomas | Pilocytic astrocytoma (grade I) | 1 |
Pleomorphic xanthoastrocytoma (grade II) | 1 | |
Anaplastic pleomorphic xanthoastrocytoma (grade III) | 1 | |
Anatomic location | Frontal | 97 |
Frontal-parietal | 15 | |
Frontal-temporal | 5 | |
Parietal | 39 | |
Parietal-occipital | 10 | |
Temporal | 84 | |
Temporal-parietal | 17 | |
Temporal-occipital | 3 | |
Occipital | 9 | |
Cerebellar hemisphere | 4 | |
Corpus callosum | 2 | |
Thalamus | 1 | |
Pituitary gland | 1 | |
Insular | 1 | |
Multicentric | 13 |