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Table 1 Epidemiological and clinical features of our cohort of patients

From: New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma

Epidemiological-clinical data

Total cohort

 

301

Gender

Male

175 pts (58.1%)

 

Female

126 pts (41.9%)

 

M:F

1.4

Age (years)

Range

20-86

 

Median

64

 

< 30 years

10 pts (3.3%)

 

≥ 30 years

291 pts (96.7%)

Diagnosis (WHO 2016)

  

Common Gliomas

Diffuse astrocytoma, IDH-wt (grade II)

6

 

Diffuse astrocytoma, IDH-mut (grade II)

10

 

Anaplastic astrocytoma, IDH-wt (grade III)

6

 

Anaplastic astrocytoma, IDH-mut (grade III)

10

 

Glioblastoma, IDH-wt (grade IV)

241

 

Glioblastoma, IDH-mut (grade IV)

10

 

Oligodendroglioma, IDH-mut and 1p/19q-codeleted (grade II)

7

 

Anaplastic oligodendroglioma, IDH-mut and 1p/19q-codeleted (grade III)

8

Uncommon Gliomas

Pilocytic astrocytoma (grade I)

1

 

Pleomorphic xanthoastrocytoma (grade II)

1

 

Anaplastic pleomorphic xanthoastrocytoma (grade III)

1

Anatomic location

Frontal

97

 

Frontal-parietal

15

 

Frontal-temporal

5

 

Parietal

39

 

Parietal-occipital

10

 

Temporal

84

 

Temporal-parietal

17

 

Temporal-occipital

3

 

Occipital

9

 

Cerebellar hemisphere

4

 

Corpus callosum

2

 

Thalamus

1

 

Pituitary gland

1

 

Insular

1

 

Multicentric

13

  1. pts, patients; wt, wildtype; mut, mutant