Fig. 2
From: New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma
Schematic representation of TERTp mutations: a TERT promoter electropherogram in case UPN#131. The arrow indicates the start point of the c.1-100_1-79dup; b TERT promoter electropherogram in case UPN#171. The arrow indicates the start point of the c.1-110_1-89dup; c Overview of all TERTp variants detected in our cases. Upper arrow: wildtype TERT core promoter with the normal location of ETS binding sites. The vertical black lines indicate the genomic positions of TERTp variants. Lower arrow: positions and types of TERTp variants and their predicted effects on transcription factors binding sites