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Table 4 Morphology parameters of GFAP and Vimentin labelled radial glia in the Down syndrome and age-matched Euploid brain

From: Assessment of radial glia in the frontal lobe of fetuses with Down syndrome

Cases PMA GFAP Vimentin
oSVZ IZ oSVZ IZ
Circularity Area (µm2) Length (µm) Circularity Area (µm2) Length (µm) Circularity Area (µm2) Length (µm) Circularity Area (µm2) Length (µm)
Age-matched euploid control
E-1 18 + 0 0.25 57.98 14.14 0.26 21.64 9.32 0.24 57.13 14.04 0.28 38.65 11.38
E-2 22 + 2 0.22 47.14 14.14 0.23 31.82 12.19 0.23 45.79 13.59 0.25 29.50 11.04
E-3 23 + 0 0.20 44.31 15.20 0.16 25.17 13.80 0.20 61.98 17.16 0.21 40.24 14.62
E-4 23 + 2 0.30 34.43 10.71 0.33 23.14 8.69 0.32 28.86 9.55 0.30 38.10 10.93
E-5 24 + 1 0.35 26.08 8.65 0.43 16.99 6.34 0.34 30.07 9.22 0.33 20.67 8.17
E-6 24 + 2 0.38 31.71 9.12 0.37 22.57 8.09 x x x x x x
Down syndrome
DS-1 15 + 6 0.31 49.33 12.44 0.28 42.60 11.40 0.33 32.23 10.17 0.33 24.64 8.97
DS-2 18 + 4 0.22 47.21 14.48 0.20 34.91 12.85 0.20 75.37 19.35 0.16 48.23 17.78
DS-3 19 + 5 0.31 42.52 11.81 0.33 24.87 9.54 0.27 49.87 13.82 0.32 19.80 8.36
DS-4 21 + 1 0.27 29.35 10.17 0.30 21.56 8.65 0.45 24.86 7.59 0.42 24.88 7.93
DS-5 22 + 5 0.29 60.14 13.30 0.27 37.66 13.88 0.32 49.83 13.39 0.33 47.42 13.01
  1. Length, Area and Circularity measured in the oSVZ and IZ across mid-gestation. X; Not assessed