Fig. 2

Insoluble tau levels are significantly reduced in P301S brains. a In cortex, insoluble tau levels (INS) were significantly decreased in the scFvMC1 treated group (n = 6) compared to the control cohort (n = 6) (*p < 0.05; **p < 0.01; non parametric Mann-Whitney test). b In HB, insoluble tau showed a trend of reduction in the scFvMC1 group (n = 6) compared to the controls (n = 6): total tau (p = 0.0931), pThr231(p = 0.0931), pSer202 (p = 0.1320), pSer396/404 (p = 0.5887). Graphs are expressed as % Control, and means +/− SEM