Fig. 6

Soleus muscle of Hom mice at the ultrastructural level. a Longitudinal semithin section of Epon embedded soleus muscle of an adult Hom mouse stained with toluidine blue. Shown is a section with two neighboring darkly stained macrolesions (arrows). Note numerous elongated and swollen mitochondria (arrowheads). b Transmission electron microscopy of an ultrathin section similar to the section shown in A. Depicted are two macrolesions (arrows) surrounded by normally appearing myofibrils. Also, here many elongated and swollen mitochondria are observed (arrowheads). c A section containing three microlesions (arrows). The boxed microlesions are shown enlarged in panels d_i-d_iii. Bars: 5 μm (a, c), 10 μm (b), 2.5 μm (d_i-d_iii)