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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice

Fig. 6

qPCR validation of hippocampal mRNA expression for LT synthesis related genes: a Microglia ablation in WT and APP-PS1 mice resulted in significantly lower mRNA expression of Alox5ap and Alox5. b Expression of cysteinyl-LT receptor CysLTR1 was significantly decreased upon microglia ablation in WT and APP-PS1 mice. One-way analysis of variance with Bonferroni’s multiple comparison test was used. P-values < 0.05 were considered significant. Data are shown as mean with SEM

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Acta Neuropathologica Communications

ISSN: 2051-5960

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