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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Molecular identification of CNS NB-FOXR2, CNS EFT-CIC, CNS HGNET-MN1 and CNS HGNET-BCOR pediatric brain tumors using tumor-specific signature genes

Fig. 8

Morphology and immunophenotype of CNS-HGNT BCOR tumors. a Micronecrosis. b Papillary architecture and microcystic background. c Papillary structure with uniform, small cells arranged around eosinophilic acellular cores. d A few GFAP-immunopositive reactive astrocytes. e Strong GFAP immunoreactivity in reactive astroglial cells and tumor background. f Intense GFAP positivity around blood vessels. g Focal immunonegativity for GFAP. h A few tiny GFAP positive glial processes. i High Ki67 proliferation index in unusual malignant papillary neuroepithelial tumor. The scale bars: a - 150 μm; b, g - 100 μm; c - 30 μm; d-f, h, i - 50 μm

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