From: Molecular and clinicopathologic features of gliomas harboring NTRK fusions
Patient characteristics | Total, n (%) |
---|---|
Total Number of Patients | 42 (100%) |
Demographics | |
 Sex | |
  Male | 24 (57.1%) |
  Female | 18 (42.9%) |
 Age, median (range), years | 24 (<1-81) |
  Infantile (≤1), n (%) | 7 (16.7%) |
  Pediatric (>1 to ≤18), n (%) | 13 (31.0%) |
  Adult (>18), n (%) | 22 (52.4%) |
Radiology | |
 Location | |
  Hemispheric | 28 (66.7%) |
  Brainstem/spinal cord | 4 (9.5%) |
  Cerebellar | 3 (7.1%) |
  Gliomatosis pattern/widespread | 3 (7.1%) |
  Optic nerve/suprasellar/deep grey nuclei | 2 (4.8%) |
  Other/unknown | 2 (4.8%) |
Survival Data (n=21: 4 infantile, 9 pediatric, 8 adult) (cases without any available follow-up data excluded) | |
 Deaths | 6 (28.6% of all cases; all HG) |
  Infantile | 2 (50%) |
  Pediatric | 0 (0%) |
  Adult | 4 (50%) |
 Tumor Recurrence/Progression | 11 (57.9%; 6 HG, 1 LG, 4 of certain WHO grade)a |
  Infantile | 2 (100%)a |
  Pediatric | 5 (55.6%) |
  Adult | 4 (50%) |
 Follow-up, median (range), months | 23 (4-189)a |