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Table 1 Clinicopathologic characteristics

From: Molecular and clinicopathologic features of gliomas harboring NTRK fusions

Patient characteristics Total, n (%)
Total Number of Patients 42 (100%)
Demographics
 Sex
  Male 24 (57.1%)
  Female 18 (42.9%)
 Age, median (range), years 24 (<1-81)
  Infantile (≤1), n (%) 7 (16.7%)
  Pediatric (>1 to ≤18), n (%) 13 (31.0%)
  Adult (>18), n (%) 22 (52.4%)
Radiology
 Location
  Hemispheric 28 (66.7%)
  Brainstem/spinal cord 4 (9.5%)
  Cerebellar 3 (7.1%)
  Gliomatosis pattern/widespread 3 (7.1%)
  Optic nerve/suprasellar/deep grey nuclei 2 (4.8%)
  Other/unknown 2 (4.8%)
Survival Data (n=21: 4 infantile, 9 pediatric, 8 adult)
(cases without any available follow-up data excluded)
 Deaths 6 (28.6% of all cases; all HG)
  Infantile 2 (50%)
  Pediatric 0 (0%)
  Adult 4 (50%)
 Tumor Recurrence/Progression 11 (57.9%; 6 HG, 1 LG, 4 of certain WHO grade)a
  Infantile 2 (100%)a
  Pediatric 5 (55.6%)
  Adult 4 (50%)
 Follow-up, median (range), months 23 (4-189)a
  1. aExcludes 2 infantile tumors diagnosed at autopsy
  2. HG High histologic grade, LG Low histologic grade
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