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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Molecular and clinicopathologic features of gliomas harboring NTRK fusions

Fig. 6

Methylation clustering analysis t-distributed stochastic neighbor embedding (tSNE) plots: of the 18 NTRK-fused gliomas with methylation profiling data, only two matched with high confidence to known methylation class families. (a) Case 3 (histologic diagnosis: high-grade glioma with features of pleomorphic xanthoastrocytoma (PXA)) matched to methylation class PXA, and (b) case 14 (histologic diagnosis: glioblastoma) matched to methylation class infantile hemispheric glioma (IHG). LGG, GG, low grade glioma, ganglioglioma; LGG, PA/GG ST, low grade glioma, pilocytic astrocytoma ganglioglioma spectrum in supratentorial compartment

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