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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: The pediatric supratentorial MYCN-amplified high-grade gliomas methylation class presents the same radiological, histopathological and molecular features as their pontine counterparts

Fig. 2

Results of the systematic review of supratentorial molecular subgroups of pediatric HGG. a There was no significant difference in terms of progression-free survival (PFS) between HGG-MYCN, HGG-RTKI, supratentorial H3 K27M-mutant HGG and H3 G34-mutant HGG in univariate analysis (p = 0.421). b There was no significant difference in terms of progression-free survival (PFS) between HGG-MYCN, HGG-RTKI, supratentorial H3 K27M-mutant HGG and H3 G34-mutant HGG in univariate analysis (p = 0.109). c There was a significant difference in terms of overall survival (OS) between supratentorial HGG-MYCN and pontine HGG-MYCN in univariate analysis (p < 0.001)

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