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Table 2 Clinico-radiological features of 46 low-grade (LG) intramedullary astrocytomas

From: Clinical, radiological and molecular characterization of intramedullary astrocytomas

Variable

Grade I

Grade II

LG

Fisher test1 (except 2)

n = 26 (%)

n = 17 (%)

n = 3 (%)

Age (mean 33, range 4–73 years)

  < 18 years

7 (27)

2 (12)

1 (33)

p = 0.211

  ≥ 18 years

19 (73)

15 (88)

2 (67)

Gender

 male

12 (46)

9 (35)

3 (100)

p = 0.451

 female

14 (54)

8 (31)

0 (0)

Tumor location

 Cervical

8 (31)

5 (29)

1 (33)

NA2

 Cervico-Thoracic

10 (38)

5 (29)

1 (33)

 Thoracic

5 (19)

7 (41)

0 (0)

 Thoraco-Lumbar

2 (8)

0 (0)

1 (33)

 Lumbar

1 (4)

0

0

Infiltration

 Well-delienated

6 (33)

5 (29)

0 (0)

p = 0.546

 Infiltrative

12 (67)

12 (71)

1 (100)

 No data

8

0

2

 

Contrast enhancement

 No

1 (4)

7 (41)

1 (50)

 

 Yes

25 (96)

10 (59)

1 (50)

p = 0.004

 No data

0

0

1

 

Extent of surgical resection

 Gross total resection

5 (19)

2 (12)

0 (0)

p = 0.0113

 Partial resection

17 (65)

6 (35)

1 (33)

 Biopsy

4 (15)

9 (53)

2 (67)

 

Adjuvant treatments

 No

24 (92)

17 (100)

3 (100)

p = 0.359

 Yes

2 (8)

0

0

  1. 1The three LG cases for which grade I or grade II diagnosis could not be made and category “No data” were excluded from the statistical analyses; 2chi-square test; 3comparison of biopsy and surgical resection (gross total and partial); NA Not applicable