Table 1 Summary of all cases used in this study. See supplementary data for subgroup analyses
From: Quantitative patterns of motor cortex proteinopathy across ALS genotypes
Genotype | n = | With FTD | Sex | Age (Years) | PMD (Hours) | Fixation (Weeks) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
M | F | Range | Mean | Std. Dev. | Range | Mean | Std. Dev. | Range | Mean | Std. Dev. | |||
Control | 17 | 0 | 10 | 7 | 36–95 | 62.5 | 14.0 | 18–73 | 42.5 | 16.0 | 0.2–32 | 7.1 | 9.2 |
Sporadic | 39 | 7 | 21 | 18 | 44–90 | 65.5 | 11.7 | 24–120 | 47.7 | 22.5 | 0.2–28 | 5.9 | 8.5 |
C9ORF72a | 18 | 5 | 11 | 7 | 42–76 | 60.6 | 9.4 | 4–96 | 47.5 | 30.5 | 0.2–17 | 7.5 | 4.8 |
SOD1b | 11 | 0 | 3 | 8 | 34–78 | 55.9 | 14.7 | 5–96 | 39.0 | 31.9 | 3–20 | 11.8 | 5.8 |
FUSc | 9 | 0 | 4 | 5 | 18–64 | 37.9 | 15.2 | 19–72 | 47.0 | 19.5 | 2–45 | 12.6 | 13.7 |
CHMP2Bd | 2 | 0 | 1 | 1 | 51–69 | 60.0 | 12.7 | 12–22 | 17.0 | 7.1 | 3–4.5 | 3.8 | 1.1 |
HNRNPA1e | 1 | 0 | 0 | 1 | 62 | 62.0 | – | 48 | 48.0 | – | 12.0 | 12.0 | – |
OPTNf | 1 | 0 | 1 | 0 | 54 | 54.0 | – | 72 | 72.0 | – | 12.0 | 12.0 | – |
TARDBPg | 1 | 0 | 1 | 0 | 57 | 57.0 | – | 48 | 48.0 | – | 9.0 | 9.0 | – |