Skip to main content
Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Transmission characteristics of heterozygous cases of Creutzfeldt-Jakob disease with variable abnormal prion protein allotypes

Fig. 5

Spongiform change and PrPSc deposition differ in the brains of tg66 mice inoculated with cases of MV1 + 2C with different PrPSc allotype ratios. a H&E staining of tg66 mice inoculated with MV1 + 2C cases 3 (183 dpi) and 4 (479 dpi). The mean percentage of PrPSc-M129 in each sample is given under the case number. b PrPSc staining using the mouse monoclonal anti-PrP antibody 3F4 conjugated to biotin. The fields are matched to those shown in panel a. The brain regions shown are indicated in the middle of the figure. For all panels, scale bar = 50 μm

Back to article page
\