Fig. 2
Lack of correlation between PrPSc-M129 or total PrPSc abundance versus disease incubation time in transgenic mice inoculated with MV heterozygous CJD brain homogenate. a The y-axis shows the percentage of total PrPSc which is PrPSc-M129 versus disease incubation time in days post-infection (DPI) for tg66 (left panel) and tgRM (right panel) mice. Mean + SD is shown for each CJD sample (closed circles) and the MM1 sCJD control (open circle). The results of the linear regression analysis are represented by the line and the R2 value is given in the lower left corner of each graph. b The y-axis shows the spectral count (SpC) of the total PrPSc in the sample versus disease incubation times in DPI for tg66 (left panel) and tgRM (right panel) mice. Figure legend and linear regression analysis are the same as in panel a