Fig. 1
Survival curves for tg66 and tgRM mice inoculated with MV heterozygous CJD brain homogenate containing variable levels of PrPSc-M129. Survival curves for mice inoculated with (a) MV1 + 2C or (b) MV2K + 2C sCJD. The percentage of PrPSc-M129 for each case inoculated is shown in parentheses to the right of the case number. Solid lines = tg66 mice; dashed lines = tgRM mice. Survival curves for (c) tg66 or (d) tgRM mice inoculated with MV2K CJD. The percentage of PrPSc-M129 for each case inoculated is shown in parentheses to the right of the case number. Solid lines = sCJD cases; dashed lines = iCJD cases