Fig. 1

Protein levels and mRNA levels of active zone proteins and Bassoon. a Western blots showing the expression of CASK, Mint1, Rim1, ERC and Munc 13–1 Bassoon in the cortex and the striatum of 40w old R6/1 and WT mice. b Bassoon mRNA levels in 40w old R6/1 and WT mouse cortex. * p < 0.05, n = 9 / genotype. c Representative Western blot of Bassoon at 7, 16 and 40 weeks. d Bassoon protein levels in R6/1 and WT mice at 7, 16 and 40 weeks of age. *p < 0.05 n = 4 / genotype and age