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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Transmission of ALS pathogenesis by the cerebrospinal fluid

Fig. 4

Infusion of ALS-CSF induced neuroinflammation. (a-d) Glial activation. Representative confocal images of the spinal cord sections stained with GFAP (a) and Galectin-3 (c). Expression patterns and quantification of the immunoblots for GFAP protein (b) as well as Galectin-3 (d) protein in the spinal cord lysates. (e-g) Expression patterns and quantification of the immunoblots for immune markers: phosphorylated p65 subunit of NF-κB (e), Chit-1 (f) and Arginase-1 (g) in the spinal cord lysates. Data are mean ± SEM. (*p ≤ 0.05, **p ≤ 0.01, and **** p ≤ 0.0001) and fold changes are calculated when compared to NALS. (n = 3) Scale bar = 20 μm

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