Fig. 3From: Differential gene methylation and expression of HOX transcription factor family in orbitofacial neurofibromaHOX family transcription factors are hypomethylated in orbitofacial neurofibromas. Genomic maps demonstrating promoter hypomethylation of HOXC8, HOXC6, HOXC4 and HOXA6 in orbitofacial neurofibromas. The x-axis corresponds to the chromosome location of individual HOX genes differentially methylated regions (DMR) in or near the promoter in orbitofacial NF (pink dots and plot) vs non-orbitofacial NF (blue dots and plot). The y-axis demonstrates the methylation status near the gene of interest as Beta values. Beta values closest to 0 denote decreased methylation, and values closest to 1 increased methylation. HOX transcription factor genes are relatively hypomethylated in orbitofacial NF compared to non-orbitofacial NFBack to article page