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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Meningomyeloencephalitis secondary to Mycobacterium haemophilum infection in AIDS

Fig. 2

Microscopic findings of this patient. a-b Representative micrograph of the AFB and LH&E of the occipitopontine tract. c-d Representative micrographs of the AFB and LH&E of the corticospinal/ corticobulbar tract. e-f Representative micrographs of the AFB and LH&E of the frontopontine tract. g Whole section image of the left half midbrain at the level of the superior cerebellar peduncle. h-i Representative image of the most severely inflamed region in the midbrain highlighting extensive lymphohistiocytic infiltrate and abundant AFB within macrophages. j Representative image showing macrophages containing myelin and neuromelanin in the substantia nigra. k Whole section image of the left upper pons. l Micrograph of the ventral rostral medulla. m Whole section image of thoracic cord. n LH&E stain highlights ventral horn neuron surrounded by lymphohistiocytic inflammation. o Macrophages containing AFB surround apparently normal ventral horn neurons. Area outlined by dashed lines indicate arterial territories supplying respective brainstem levels (g, k, l). Scale bars: a-f, h: 100 μm, i-j, n-o: 50 μm. The high resolution source of Figure 2 is available as Additional file1

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