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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes

Fig. 6

LATE-NC in non-AD, p-preAD, ADTDP-, ADTDP + CTF and ADTDP + FL cases. Most non-AD cases have no LATE-NC. ADTDP- have no LATE-NC. The majority of p-preAD and ADTDP + CTF cases present LATE-NC restricted to the medial temporal lobe (stage 2). One ADTDP + CTF case was not considered for the LATE-NC classification due to being considerably younger, despite presenting TDP-43 pathology. On the other hand, nearly half of ADTDP + FL cases have LATE-NC stage 2 and the remaining cases present more widespread LATE-NC, extended to the frontal cortex (stage 3)

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