Fig. 3
From: Common gene expression signatures in Parkinson’s disease are driven by changes in cell composition
Functional enrichment. The treemap shows the concordant enriched pathways between PW and NBB cohorts accounting for experimental covariates and MGPs (same direction of gene expression change and FDR < 0.05). Pathways are grouped with a white border if their gene overlap is above 0.5 (Szymkiewicz–Simpson coefficient). Darker shades of red/blue represent lower enrichment p-values for up−/down-regulated pathways. Sizes of the rectangles are proportional to pathway sizes